The average bus between Milan and Isola del Liri takes 15h 29m and the fastest bus takes 10h 29m. There is at least one bus per day from Milan to Isola del Liri. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Milan and Isola del Liri. The earliest departure is at 12:45 PM in the afternoon, and the last departure from Milan is at 11:20 PM which arrives into Isola del Liri at 9:49 AM. All services require a transfer at FROSINONE | Piazza Pertini # f3486 and take an average of 15h 29m. The schedules shown below are for the next available departures.
Arrives next day


20h 4m • 2 changes
Arrives next day


10h 29m • 2 changes
Arrives next day


18h 42m • 2 changes
Arrives next day


10h 29m • 2 changes
Want to know about travelling from Milan to Isola del Liri? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Milan to Isola del Liri. However, there are services departing from Milan station and arriving at Isola del Liri station via Frosinone. The journey, including transfers, takes approximately 15h 29m.
Milan to Isola del Liri bus services, operated by FlixBus, depart from Milano, San Donato M3 station.
Milan to Isola del Liri bus services, operated by FlixBus, arrive at Frosinone station.
The distance between Milan and Isola del Liri is 549.2 km. The road distance is 670 km.
FlixBus operates a bus from Milano, San Donato M3 to Frosinone once daily. Tickets cost €55–95 and the journey takes 8h.