The average bus between Milan and Ossola takes 5h 29m and the fastest bus takes 2h 44m. The bus service runs several times per day from Milan to Ossola. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Milan and Ossola. The earliest departure is at 7:25 AM in the morning, and the last departure from Milan is at 9:25 PM which arrives into Ossola at 8:54 AM. All services require a transfer at Domodossola and take an average of 5h 29m. The schedules shown below are for the next available departures.

2h 44m • 1 change

4h 34m • 1 change
Arrives next day

11h 29m • 1 change

2h 44m • 1 change

4h 34m • 1 change
Arrives next day

11h 29m • 1 change
Want to know about travelling from Milan to Ossola? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Milan to Ossola. However, there are services departing from Milan station and arriving at Ossola station via Domodossola. The journey, including transfers, takes approximately 5h 29m.
Milan to Ossola bus services, operated by Trenord, depart from Milano Centrale station.
Milan to Ossola bus services, operated by Trenord, arrive at Premia - Frazione Piedilago station.
The distance between Milan and Ossola is 111.9 km. The road distance is 165 km.
You can take a bus from Milano Centrale to Ossola via Domodossola, Domodossola - Stazione Ferroviaria, and Premia - Frazione Piedilago in around 3h 34m.