The average bus between Milan and Provincia di Siena (Region) takes 6h 21m and the fastest bus takes 5h 57m. The bus service runs several times per day from Milan to Provincia di Siena (Region). The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Milan and Provincia di Siena (Region). The earliest departure is at 1:10 AM at night, and the last departure from Milan is at 2:45 PM which arrives into Provincia di Siena (Region) at 8:47 PM. All services require a transfer at Siena and take an average of 6h 21m. The schedules shown below are for the next available departures.

5h 57m • 1 change

6h 31m • 1 change

6h • 1 change

6h 2m • 1 change

5h 57m • 1 change

6h 31m • 1 change

6h • 1 change

6h 2m • 1 change

6h 47m • 1 change

8h 3m • 1 change

8h 19m • 1 change

6h 2m • 1 change
Want to know about travelling from Milan to Provincia di Siena (Region)? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Milan to Provincia di Siena (Region). However, there are services departing from Milan station and arriving at Provincia di Siena (Region) station via Siena. The journey, including transfers, takes approximately 6h 21m.
Milan to Provincia di Siena (Region) bus services, operated by FlixBus, depart from Milano, San Donato M3 station.
Milan to Provincia di Siena (Region) bus services, operated by FlixBus, arrive at Siena station.
The distance between Milan and Provincia di Siena (Region) is 305.5 km. The road distance is 372 km.
FlixBus operates a bus from Milano, San Donato M3 to Siena 5 times a day. Tickets cost €28–45 and the journey takes 4h 20m.