The average bus between Milan and Quartieri Spagnoli takes 10h 42m and the fastest bus takes 10h 10m. The bus service runs several times per day from Milan to Quartieri Spagnoli. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Milan and Quartieri Spagnoli. The earliest departure is at 1:10 AM at night, and the last departure from Milan is at 11:20 PM which arrives into Quartieri Spagnoli at 9:30 AM. All services require a transfer at Napoli P.zza Garibaldi and take an average of 10h 42m. The schedules shown below are for the next available departures.

11h 5m • 1 change
11h • 1 change
11h 4m • 1 changeArrives next day

10h 15m • 1 change
11h 5m • 1 change
11h • 1 change
11h 4m • 1 changeArrives next day

10h 20m • 1 changeWant to know about travelling from Milan to Quartieri Spagnoli? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Milan to Quartieri Spagnoli. However, there are services departing from Milano, San Donato M3 station and arriving at Napoli P.zza Garibaldi station via Napoli P.zza Garibaldi station. The journey, including transfers, takes approximately 10h 42m.
Milan to Quartieri Spagnoli bus services, operated by FlixBus, depart from Milano, San Donato M3 station.
Milan to Quartieri Spagnoli bus services, operated by FlixBus, arrive at Napoli P.zza Garibaldi station.
The distance between Milan and Quartieri Spagnoli is 657.4 km. The road distance is 771 km.
FlixBus operates a bus from Milano, San Donato M3 to Napoli P.zza Garibaldi 3 times a day. Tickets cost €65–110 and the journey takes 10h 25m.