The average bus between Milan and Ruffré-Mendola takes 7h 9m and the fastest bus takes 4h 59m. The bus service runs several times per day from Milan to Ruffré-Mendola. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Milan and Ruffré-Mendola. The earliest departure is at 8:00 AM in the morning, and the last departure from Milan is at 8:10 PM which arrives into Ruffré-Mendola at 6:55 AM. All services require a transfer at Bolzano South and take an average of 7h 9m. The schedules shown below are for the next available departures.

5h 44m • 1 change

4h 59m • 1 change
Arrives next day

14h 25m • 1 change

5h 44m • 1 change

4h 59m • 1 change
Arrives next day

10h 45m • 1 change
Want to know about travelling from Milan to Ruffré-Mendola? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Milan to Ruffré-Mendola. However, there are services departing from Milan station and arriving at Ruffré-Mendola station via Bolzano South. The journey, including transfers, takes approximately 7h 9m.
Milan to Ruffré-Mendola bus services, operated by FlixBus, depart from Milano, San Donato M3 station.
Milan to Ruffré-Mendola bus services, operated by FlixBus, arrive at Bolzano South station.
The distance between Milan and Ruffré-Mendola is 188.2 km. The road distance is 308 km.
FlixBus operates a bus from Milano, San Donato M3 to Bolzano South 4 times a day. Tickets cost €25–45 and the journey takes 4h 10m.