The average bus between Milan and Sant'Andrea takes 20h 51m and the fastest bus takes 16h 35m. The bus service runs several times per day from Milan to Sant'Andrea. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Milan and Sant'Andrea. The earliest departure is at 8:15 AM in the morning, and the last departure from Milan is at 11:05 PM which arrives into Sant'Andrea at 3:40 PM. All services require a transfer, and take on average 20h 51m. The schedules shown below are for the next available departures.
Arrives next day

24h 25m • 1 change
Arrives next day

16h 35m • 1 change
Arrives next day

24h 25m • 1 change
Arrives next day

16h 35m • 1 change
Want to know about travelling from Milan to Sant'Andrea? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Milan to Sant'Andrea. However, there are services departing from Milan station and arriving at Sant'Andrea station via Lecce. The journey, including transfers, takes approximately 20h 51m.
Milan to Sant'Andrea bus services, operated by FlixBus, depart from Milano, San Donato M3 station.
Milan to Sant'Andrea bus services, operated by FlixBus, arrive at Lecce station.
The distance between Milan and Sant'Andrea is 950.1 km. The road distance is 1,076 km.
FlixBus operates a bus from Milano, San Donato M3 to Lecce once daily. Tickets cost €90–150 and the journey takes 13h 15m.