The average bus between Milan and Sestri Ponente takes 2h 41m and the fastest bus takes 2h 11m. The bus service runs several times per day from Milan to Sestri Ponente. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Milan and Sestri Ponente. The earliest departure is at 8:15 AM in the morning, and the last departure from Milan is at 10:00 PM which arrives into Sestri Ponente at 12:13 AM. All services require a transfer at Genoa and take an average of 2h 41m. The schedules shown below are for the next available departures.

2h 46m • 1 change

2h 57m • 1 change
Arrives next day

2h 11m • 1 change

2h 41m • 1 change

2h 44m • 1 change

2h 46m • 1 change

2h 37m • 1 change

2h 44m • 1 change

2h 37m • 1 change

2h 46m • 1 change

2h 57m • 1 change

2h 44m • 1 change

2h 37m • 1 change

2h 46m • 1 change

2h 51m • 1 change

2h 41m • 1 change

2h 44m • 1 change

2h 37m • 1 change

2h 46m • 1 change

2h 44m • 1 change

2h 50m • 1 change

2h 38m • 1 change

2h 49m • 1 change

2h 44m • 1 change

2h 50m • 1 change

2h 49m • 1 change

2h 40m • 1 change
Want to know about travelling from Milan to Sestri Ponente? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Milan to Sestri Ponente. However, there are services departing from Milan station and arriving at Sestri Ponente station via Genoa. The journey, including transfers, takes approximately 2h 41m.
Milan to Sestri Ponente bus services, operated by FlixBus, depart from Milano, Autostazione Lampugnano station.
Milan to Sestri Ponente bus services, operated by FlixBus, arrive at Genoa station.
The distance between Milan and Sestri Ponente is 118.6 km. The road distance is 157 km.
FlixBus operates a bus from Milano, Autostazione Lampugnano to Genoa every 4 hours. Tickets cost €12–20 and the journey takes 2h 5m. BlaBlaCar Bus also services this route 4 times a day.