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Milan to Sicily buses

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Trip Overview

The bus between Milan and Sicily takes 22h 18m. The bus runs, on average, 6 times per week from Milan to Sicily. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

22h 18m
Duration
1,596 km
Distance
€159
Average price
6 times a week
Frequency

Milan to Sicily bus times

Buses run 6 times a week between Milan and Sicily. The earliest departure is at 1:05 PM in the afternoon, and the last departure from Milan is at 1:05 PM which arrives into Sicily at 11:27 AM. All services require a transfer at Palermo and take an average of 22h 18m. The schedules shown below are for the next available departures.

Departing Monday, October 12, 2026

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    Arrives next day

    FlixBusAMAT Palermo S.p.A.22h 18m • 1 change

Departing Tuesday, October 13, 2026

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    Arrives next day

    FlixBusAMAT Palermo S.p.A.22h 18m • 1 change

Departing Wednesday, October 14, 2026

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    Arrives next day

    FlixBusAMAT Palermo S.p.A.22h 18m • 1 change

Departing Thursday, October 15, 2026

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    Arrives next day

    FlixBusAMAT Palermo S.p.A.22h 18m • 1 change

Departing Friday, October 16, 2026

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    Arrives next day

    FlixBusAMAT Palermo S.p.A.22h 18m • 1 change

Departing Saturday, October 17, 2026

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    Arrives next day

    FlixBusAMAT Palermo S.p.A.22h 22m • 1 change

Frequently asked questions

Want to know about travelling from Milan to Sicily? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Milan to Sicily.ExpandLaunch map view
  • Distance: 1,595.7 km
  • Duration: 22h 18m

What companies run services between Milan, Italy and Sicily, Italy?

FlixBus operates a bus from Milano, Autostazione Lampugnano to Palermo once daily. Tickets cost €130–200 and the journey takes 21h 55m.

Operators