The average bus between Milazzo and Siracusa takes 3h 28m and the fastest bus takes 3h 20m. The bus service runs several times per day from Milazzo to Siracusa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Milazzo and Siracusa. The earliest departure is at 5:30 AM in the morning, and the last departure from Milazzo is at 6:15 PM which arrives into Siracusa at 9:50 PM. All services require a transfer, and take on average 3h 28m. The schedules shown below are for the next available departures.

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3h 25m • 1 change

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3h 25m • 1 change
Want to know about travelling from Milazzo to Siracusa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Milazzo to Siracusa. However, there are services departing from Milazzo station and arriving at Siracusa station via Catania Airport. The journey, including transfers, takes approximately 3h 28m.
Milazzo to Siracusa bus services, operated by Giuntabus, depart from Milazzo Port Stop station.
Milazzo to Siracusa bus services, operated by Giuntabus, arrive at Siracusa - Corso Umberto station.
Book your Milazzo to Siracusa bus tickets online with Giuntabus, Interbus and Azienda Siciliana Trasporti.
The distance between Milazzo and Siracusa is 128.1 km. The road distance is 198 km.
You can take a bus from Milazzo Port Stop to Siracusa - Corso Umberto via Catania Airport in around 3h 26m.