The average bus between Mildenhall and Southampton takes 6h 18m and the fastest bus takes 5h 35m. The bus service runs several times per day from Mildenhall to Southampton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Mildenhall and Southampton. The earliest departure is at 3:00 AM at night, and the last departure from Mildenhall is at 5:15 PM which arrives into Southampton at 11:35 PM. All services require a transfer, and take on average 6h 18m. The schedules shown below are for the next available departures.

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6h • 1 changeWant to know about travelling from Mildenhall to Southampton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Mildenhall to Southampton. However, there are services departing from Mildenhall station and arriving at Southampton station via Heathrow Terminal 5. The journey, including transfers, takes approximately 6h 18m.
Mildenhall to Southampton bus services, operated by National Express, depart from Bus Station.
Mildenhall to Southampton bus services, operated by National Express, arrive at Coach Station.
Book your Mildenhall to Southampton bus tickets online with National Express.
The distance between Mildenhall and Southampton is 207.9 km. The road distance is 278 km.
You can take a bus from Bus Station to Coach Station via Heathrow Terminal 5 in around 5h 44m.