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Millsboro to Niagara Falls buses

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Trip Overview

The average bus between Millsboro and Niagara Falls takes 33h 43m and the fastest bus takes 22h 38m. The bus runs, on average, 2 times per week from Millsboro to Niagara Falls. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

33h 43m
Duration
643 mi
Distance
$112
Average price
Twice a week
Frequency

Millsboro to Niagara Falls bus times

Buses run twice a week between Millsboro and Niagara Falls. The earliest departure is at 7:01 PM in the evening, and the last departure from Millsboro is at 8:51 PM which arrives into Niagara Falls at 5:40 PM. All services require a transfer at Rehoboth P-N-R @ Country Club Rd and take an average of 33h 43m. The schedules shown below are for the next available departures.

Departing Saturday, November 7, 2026

  •  → 

    Arrives next day

    DART First StateDART First StateGreyhound USAFlixbus USA22h 38m • 3 changes
  •  → 

    Arrives +2 days

    DART First StateDART First StateGreyhound USAFlixbus USA44h 48m • 3 changes

Frequently asked questions

Want to know about travelling from Millsboro to Niagara Falls? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Millsboro to Niagara Falls.ExpandLaunch map view
  • Distance: 643.2 mi
  • Duration: 33h 43m

What companies run services between Millsboro, DE, USA and Niagara Falls, NY, USA?

You can take a bus from Railroad St @ Central Alley to Niagara Falls USA via Rehoboth P-N-R @ Country Club Rd, Wilmington Tc, Wilmington Bus Station, and Newark Penn Station in around 16h 55m.

Operators