Bus Milpitas to Santa Cruz from $22 | Tickets & Timetables

Milpitas to Santa Cruz buses

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Trip Overview

The average bus between Milpitas and Santa Cruz takes 2h 2m and the fastest bus takes 1h 35m. There is an hourly bus service from Milpitas to Santa Cruz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2h 2m
Duration: 40 mi
Distance: $22
Average price: Hourly
Frequency

Line 66 bus, bus

best

Take the bus from Main & Serra to 2nd & Santa Clarabus 66
Take the bus from Diridon Station to Soquel Ave & Frontbus 17

1h 56m

$14–25

Milpitas to Santa Cruz bus times

Buses run hourly between Milpitas and Santa Cruz. The earliest departure is at 5:25 AM in the morning, and the last departure from Milpitas is at 10:18 PM which arrives into Santa Cruz at 12:17 AM. All services require a transfer at 2nd & Santa Clara and take an average of 2h 2m. The schedules shown below are for the next available departures.

Departing Monday, August 17, 2026

11:06 AM → 1:09 PM
2h 2m • 2 changes
1:04 PM → 3:09 PM
2h 4m • 2 changes
1:47 PM → 3:38 PM
1h 50m • 2 changes
2:29 PM → 4:38 PM
2h 8m • 2 changes
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Departing Tuesday, August 18, 2026

5:25 AM → 7:05 AM
1h 39m • 2 changes
6:17 AM → 8:01 AM
1h 43m • 2 changes
6:58 AM → 8:56 AM
1h 57m • 2 changes
7:26 AM → 9:31 AM
2h 4m • 2 changes
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Departing Wednesday, August 19, 2026

5:25 AM → 7:05 AM
1h 39m • 2 changes
6:17 AM → 8:01 AM
1h 43m • 2 changes
6:58 AM → 8:56 AM
1h 57m • 2 changes
7:26 AM → 9:31 AM
2h 4m • 2 changes
Show more

Frequently asked questions

Want to know about travelling from Milpitas to Santa Cruz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.