The average bus between Milton Keynes and Manchester Piccadilly Station takes 3h 51m and the fastest bus takes 3h 5m. There is a bus service every few hours from Milton Keynes to Manchester Piccadilly Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Milton Keynes and Manchester Piccadilly Station. The earliest departure is at 12:10 AM at night, and the last departure from Milton Keynes is at 11:10 PM which arrives into Manchester Piccadilly Station at 2:15 AM. All services require a transfer at Milton Keynes Coachway and take an average of 3h 51m. The schedules shown below are for the next available departures.

3h 22m • 1 change

3h 32m • 1 change

3h 22m • 1 change

3h 32m • 1 change

6h 5m • 1 change

3h 22m • 1 change

3h 22m • 1 change

3h 52m • 1 change

6h 5m • 1 change

6h 9m • 1 change

3h 29m • 1 change

3h 22m • 1 change
Want to know about travelling from Milton Keynes to Manchester Piccadilly Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Milton Keynes to Manchester Piccadilly Station. However, there are services departing from Milton Keynes station and arriving at Manchester Piccadilly Station station via Manchester Central Coach Station station. The journey, including transfers, takes approximately 3h 51m.
Milton Keynes to Manchester Piccadilly Station bus services, operated by Arriva UK, depart from Milton Keynes Coachway station.
Milton Keynes to Manchester Piccadilly Station bus services, operated by Arriva UK, arrive at Manchester Central Coach Station.
The distance between Milton Keynes and Manchester Piccadilly Station is 188 km. The road distance is 253 km.
National Express operates a bus from Milton Keynes Coachway to Manchester Central Coach Station every 30 minutes. Tickets cost £29–70 and the journey takes 3h 50m.