Milton Keynes to Southampton Buses

Milton Keynes to Southampton buses

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Trip Overview

The average bus between Milton Keynes and Southampton takes 5h 35m and the fastest bus takes 4h 30m. The bus service runs several times per day from Milton Keynes to Southampton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 35m
Duration: 129 mi
Distance: £22
Average price: Every 3 hours
Frequency

Bus

best

Take the bus from The Point to Airport Bus Stationbus Mk1
Take the bus from Airport Bus Station to Heathrow Central Bus Stationbus 230 / ...
Take the bus from Heathrow Central Bus Station to Coach Stationbus 032 / ...

4h 35m

£18–31

Milton Keynes to Southampton bus times

Buses run every 3 hours between Milton Keynes and Southampton. The earliest departure is at 6:25 AM in the morning, and the last departure from Milton Keynes is at 10:20 PM which arrives into Southampton at 8:55 AM. All services require a transfer at Airport Bus Station and take an average of 5h 35m. The schedules shown below are for the next available departures.

Departing Monday, October 19, 2026

5:46 PM → 10:20 PM
4h 34m • 2 changes
8:20 PM → 1:00 AM
Arrives next day
4h 40m • 2 changes
10:20 PM → 9:10 AM
Arrives next day
10h 50m • 2 changes

Departing Tuesday, October 20, 2026

6:46 AM → 11:20 AM
4h 34m • 2 changes
7:41 AM → 1:00 PM
5h 19m • 2 changes
9:46 AM → 2:20 PM
4h 34m • 2 changes
10:46 AM → 3:55 PM
5h 9m • 2 changes
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Departing Wednesday, October 21, 2026

6:46 AM → 11:20 AM
4h 34m • 2 changes
7:41 AM → 1:00 PM
5h 19m • 2 changes
9:46 AM → 2:20 PM
4h 34m • 2 changes
10:46 AM → 3:55 PM
5h 9m • 2 changes
Show more

Departing Thursday, October 22, 2026

6:46 AM → 11:20 AM
4h 34m • 2 changes
7:41 AM → 1:00 PM
5h 19m • 2 changes
9:46 AM → 2:20 PM
4h 34m • 2 changes
10:46 AM → 3:55 PM
5h 9m • 2 changes
Show more

Departing Friday, October 23, 2026

6:46 AM → 12:20 PM
5h 34m • 2 changes
7:41 AM → 1:45 PM
6h 4m • 2 changes
9:46 AM → 2:35 PM
4h 49m • 2 changes
10:46 AM → 3:50 PM
5h 4m • 2 changes
Show more

Departing Saturday, October 24, 2026

6:25 AM → 12:20 PM
5h 55m • 2 changes
7:46 AM → 1:30 PM
5h 44m • 2 changes
9:46 AM → 2:20 PM
4h 34m • 2 changes
10:46 AM → 3:20 PM
4h 34m • 2 changes
Show more

Frequently asked questions

Want to know about travelling from Milton Keynes to Southampton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Milton Keynes to Southampton buses

Trip Overview

Bus