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Milwaukee to Florence buses

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Trip Overview

The average bus between Milwaukee and Florence takes 29h 41m and the fastest bus takes 27h 30m. There is at least one bus per day from Milwaukee to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

29h 41m
Duration
1,108 mi
Distance
$244
Average price
Once daily
Frequency

Milwaukee to Florence bus times

Buses run once daily between Milwaukee and Florence. The service departs Milwaukee at 9:00 AM in the morning, which arrives into Florence at 13:30:00. All services require a transfer at Chicago Bus Station and take an average of 29h 41m. The schedules shown below are for the next available departures.

Departing Thursday, November 5, 2026

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    Arrives next day

    Flixbus USAFlixbus USAGreyhound USA27h 30m • 2 changes

Departing Friday, November 6, 2026

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    Arrives next day

    Flixbus USAFlixbus USAGreyhound USA27h 30m • 2 changes

Departing Saturday, November 7, 2026

  •  → 

    Arrives next day

    Flixbus USAFlixbus USAGreyhound USA27h 30m • 2 changes

Departing Sunday, November 8, 2026

  •  → 

    Arrives next day

    Flixbus USAFlixbus USAGreyhound USA27h 30m • 2 changes

Departing Monday, November 9, 2026

  •  → 

    Arrives next day

    Flixbus USAFlixbus USAGreyhound USA27h 30m • 2 changes

Frequently asked questions

Want to know about travelling from Milwaukee to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Milwaukee to Florence.ExpandLaunch map view
  • Distance: 1,107.7 mi
  • Duration: 29h 41m

What companies run services between Milwaukee, WI, USA and Florence, SC, USA?

You can take a bus from Milwaukee Intermodal Station to Florence Bus Station via Chicago Bus Station and Atlanta Bus Station in around 26h.

Operators