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Milwaukee to Jeffersonville buses

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Trip Overview

The average bus between Milwaukee and Jeffersonville takes 12h 53m and the fastest bus takes 10h 19m. The bus runs, on average, 5 times per week from Milwaukee to Jeffersonville. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

12h 53m
Duration
392 mi
Distance
$77
Average price
5 times a week
Frequency

Milwaukee to Jeffersonville bus times

Buses run 5 times a week between Milwaukee and Jeffersonville. The earliest departure is at 6:45 AM in the morning, and the last departure from Milwaukee is at 8:30 PM which arrives into Jeffersonville at 7:49 AM. All services require a transfer at Chicago Bus Station and take an average of 12h 53m. The schedules shown below are for the next available departures.

Departing Friday, November 6, 2026

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    Arrives next day

    Greyhound USAAmtrak ThruwayTransit Authority of River City22h 19m • 2 changes
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    Arrives next day

    Greyhound USAAmtrak ThruwayTransit Authority of River City10h 19m • 2 changes

Departing Saturday, November 7, 2026

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    Greyhound USAAmtrak ThruwayTransit Authority of River City10h 45m • 2 changes
  •  → 

    Arrives next day

    Greyhound USAAmtrak ThruwayTransit Authority of River City10h 19m • 2 changes

Departing Sunday, November 8, 2026

  •  → 

    Greyhound USAAmtrak ThruwayTransit Authority of River City10h 45m • 2 changes

Frequently asked questions

Want to know about travelling from Milwaukee to Jeffersonville? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Milwaukee to Jeffersonville.ExpandLaunch map view
  • Distance: 392.5 mi
  • Duration: 12h 53m

What companies run services between Milwaukee, WI, USA and Jeffersonville, IN, USA?

You can take a bus from Milwaukee Intermodal Station to Court @ Meigs via Chicago Bus Station, Chicago Union Station, Louisville, KY, and Liberty @ Roy Wilkins in around 10h 49m.

Operators