The average bus between Milwaukee and Saint Charles takes 13h 40m and the fastest bus takes 10h 39m. The bus service runs several times per day from Milwaukee to Saint Charles. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Milwaukee and Saint Charles. The earliest departure is at 6:30 AM in the morning, and the last departure from Milwaukee is at 8:35 PM which arrives into Saint Charles at 8:09 AM. All services require a transfer at Chicago Bus Station and take an average of 13h 40m. The schedules shown below are for the next available departures.
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18h 19m • 3 changes
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12h 34m • 3 changes



11h 39m • 3 changes
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17h 59m • 3 changes
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11h 34m • 3 changes



10h 39m • 3 changes
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17h 59m • 3 changes
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11h 34m • 3 changes



10h 39m • 3 changes
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17h 54m • 3 changes
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11h 34m • 3 changes



10h 39m • 3 changes
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20h 49m • 3 changes
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11h 34m • 3 changes
Want to know about travelling from Milwaukee to Saint Charles? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Milwaukee to Saint Charles. However, there are services departing from Milwaukee station and arriving at Saint Charles station via Chicago Bus Station station. The journey, including transfers, takes approximately 13h 40m.
Milwaukee to Saint Charles bus services, operated by Flixbus USA, depart from Milwaukee Intermodal Station.
Milwaukee to Saint Charles bus services, operated by Flixbus USA, arrive at St Louis Bus Station.
The distance between Milwaukee and Saint Charles is 520.2 km. The road distance is 689 km.
You can take a bus from Milwaukee Intermodal Station to 4375 Rider Trail North Sb via Chicago Bus Station, St Louis Bus Station, Civic Center Transit Center, and North Hanley Transit Center in around 10h 33m.