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Minneapolis to Florence buses

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Trip Overview

The bus between Minneapolis and Florence takes 36h 15m. The bus runs, on average, 6 times per week from Minneapolis to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

36h 15m
Duration
1,450 mi
Distance
$319
Average price
6 times a week
Frequency

Minneapolis to Florence bus times

Buses run 6 times a week between Minneapolis and Florence. The service departs Minneapolis at 12:15 AM at night, which arrives into Florence at 13:30:00. All services require a transfer at Chicago Bus Station and take an average of 36h 15m. The schedules shown below are for the next available departures.

Departing Wednesday, November 4, 2026

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    Arrives next day

    Greyhound USAFlixbus USAGreyhound USA36h 15m • 2 changes

Departing Thursday, November 5, 2026

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    Arrives next day

    Greyhound USAFlixbus USAGreyhound USA36h 15m • 2 changes

Departing Friday, November 6, 2026

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    Arrives next day

    Greyhound USAFlixbus USAGreyhound USA36h 15m • 2 changes

Departing Saturday, November 7, 2026

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    Arrives next day

    Greyhound USAFlixbus USAGreyhound USA36h 15m • 2 changes

Departing Sunday, November 8, 2026

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    Arrives next day

    Greyhound USAFlixbus USAGreyhound USA36h 15m • 2 changes

Frequently asked questions

Want to know about travelling from Minneapolis to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Minneapolis to Florence.ExpandLaunch map view
  • Distance: 1,450.1 mi
  • Duration: 36h 15m

What companies run services between Minneapolis, MN, USA and Florence, SC, USA?

You can take a bus from Minneapolis Bus Station to Florence Bus Station via Chicago Bus Station and Atlanta Bus Station in around 33h.

Operators