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Mission Viejo to Henderson buses

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Trip Overview

The average bus between Mission Viejo and Henderson takes 10h 25m and the fastest bus takes 9h 12m. The bus runs, on average, 6 times per week from Mission Viejo to Henderson. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

10h 25m
Duration
336 mi
Distance
$63
Average price
6 times a week
Frequency

Mission Viejo to Henderson bus times

Buses run 6 times a week between Mission Viejo and Henderson. The earliest departure is at 5:00 AM in the morning, and the last departure from Mission Viejo is at 5:30 AM which arrives into Henderson at 2:42 PM. All services require a transfer at Harbor-Katella and take an average of 10h 25m. The schedules shown below are for the next available departures.

Departing Monday, November 9, 2026

  •  → 

    OCTAOCTAFlixbus USARTC Southern Nevada9h 12m • 3 changes

Departing Tuesday, November 10, 2026

  •  → 

    OCTAOCTAFlixbus USARTC Southern Nevada9h 12m • 3 changes

Departing Thursday, November 12, 2026

  •  → 

    OCTAOCTAFlixbus USARTC Southern Nevada9h 12m • 3 changes

Departing Friday, November 13, 2026

  •  → 

    OCTAOCTAFlixbus USARTC Southern Nevada9h 12m • 3 changes

Departing Saturday, November 14, 2026

  •  → 

    OCTAOCTAFlixbus USARTC Southern Nevada9h 38m • 3 changes

Frequently asked questions

Want to know about travelling from Mission Viejo to Henderson? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Mission Viejo to Henderson.ExpandLaunch map view
  • Distance: 336.1 mi
  • Duration: 10h 25m

What companies run services between Mission Viejo, CA, USA and Henderson, NV, USA?

Flixbus USA operates a bus from Anaheim Regional Transportation Intermodal Center to Las Vegas Downtown 6 times a week. Tickets cost $45–75 and the journey takes 6h 30m.

Operators