The average bus between Mission Viejo and La Jolla takes 5h 25m and the fastest bus takes 3h 6m. The bus service runs several times per day from Mission Viejo to La Jolla. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Mission Viejo and La Jolla. The earliest departure is at 9:30 AM in the morning, and the last departure from Mission Viejo is at 9:30 PM which arrives into La Jolla at 6:16 AM. All services require a transfer at Santa Ana-Santiago and take an average of 5h 25m. The schedules shown below are for the next available departures.


3h 6m • 2 changes


3h 23m • 2 changes
Arrives next day


8h 33m • 2 changes


3h 6m • 2 changes


3h 23m • 2 changes
Arrives next day


8h 33m • 2 changes


3h 6m • 2 changes


3h 23m • 2 changes
Arrives next day


8h 33m • 2 changes


3h 6m • 2 changes


3h 23m • 2 changes
Arrives next day


8h 33m • 2 changes
Want to know about travelling from Mission Viejo to La Jolla? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Mission Viejo to La Jolla. However, there are services departing from Mission Viejo station and arriving at La Jolla station via San Diego Greyhound Bus Stop. The journey, including transfers, takes approximately 5h 25m.
Mission Viejo to La Jolla bus services, operated by OCTA, depart from Santa Ana Bus Stop station.
Mission Viejo to La Jolla bus services, operated by OCTA, arrive at Silverado St & Herschel Av station.
The distance between Mission Viejo and La Jolla is 91.5 km. The road distance is 181 km.
You can take a bus from Laguna Hills Trans Ctr Dock 5 to Silverado St & Herschel Av via Santa Ana-Santiago, Santa Ana Bus Stop, San Diego Greyhound Bus Stop, and Old Town Transit Center in around 4h 2m.