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Mission Viejo to Mesa buses

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Trip Overview

The bus between Mission Viejo and Mesa takes 12h 8m. The bus runs, on average, once a week from Mission Viejo to Mesa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

12h 8m
Duration
443 mi
Distance
$84
Average price
Once a week
Frequency

Mission Viejo to Mesa bus times

Buses run once a week between Mission Viejo and Mesa. The service departs Mission Viejo at 5:30 AM in the morning, which arrives into Mesa at 17:38:00. All services require a transfer at Santa Ana-Santiago and take an average of 12h 8m. The schedules shown below are for the next available departures.

Departing Thursday, October 15, 2026

  •  → 

    OCTAOCTAHoang ExpressValley MetroValley Metro12h 8m • 4 changes

Frequently asked questions

Want to know about travelling from Mission Viejo to Mesa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Mission Viejo to Mesa.ExpandLaunch map view
  • Distance: 442.6 mi
  • Duration: 12h 8m

What companies run services between Mission Viejo, CA, USA and Mesa, AZ, USA?

CBX Cross Border Express operates a bus from Santa Ana to Phoenix twice daily. Tickets cost $65–95 and the journey takes 9h 30m.

Operators