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Mission Viejo to Mesa buses

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Trip Overview

The bus between Mission Viejo and Mesa takes 37h 34m. The bus runs, on average, once a week from Mission Viejo to Mesa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

37h 34m
Duration
443 mi
Distance
$84
Average price
Once a week
Frequency

Mission Viejo to Mesa bus times

Buses run once a week between Mission Viejo and Mesa. The service departs Mission Viejo at 3:30 PM in the afternoon, which arrives into Mesa at 06:04:00. All services require a transfer at Santa Ana-Santiago and take an average of 37h 34m. The schedules shown below are for the next available departures.

Departing Saturday, November 7, 2026

  •  → 

    Arrives +2 days

    OCTAOCTAHoang ExpressValley MetroValley Metro37h 34m • 4 changes

Frequently asked questions

Want to know about travelling from Mission Viejo to Mesa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Mission Viejo to Mesa.ExpandLaunch map view
  • Distance: 442.6 mi
  • Duration: 37h 34m

What companies run services between Mission Viejo, CA, USA and Mesa, AZ, USA?

CBX Cross Border Express operates a bus from Santa Ana to Phoenix twice daily. Tickets cost $65–95 and the journey takes 9h 30m.

Operators