The average bus between Mission Viejo and San Ysidro Station takes 3h 17m and the fastest bus takes 2h 45m. The bus service runs several times per day from Mission Viejo to San Ysidro Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Mission Viejo and San Ysidro Station. The earliest departure is at 9:30 AM in the morning, and the last departure from Mission Viejo is at 11:30 PM which arrives into San Ysidro Station at 12:20 PM. All services require a transfer at Santa Ana-Santiago and take an average of 3h 17m. The schedules shown below are for the next available departures.

3h 10m • 1 change

2h 45m • 1 change
Arrives next day

2h 55m • 1 change

2h 50m • 1 change

3h 10m • 1 change

2h 45m • 1 change
Arrives next day

2h 55m • 1 change

2h 50m • 1 change

3h 10m • 1 change

2h 45m • 1 change
Arrives next day

2h 55m • 1 change

2h 50m • 1 change

3h 10m • 1 change

2h 45m • 1 change
Arrives next day

2h 55m • 1 change
Want to know about travelling from Mission Viejo to San Ysidro Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Mission Viejo to San Ysidro Station. However, there are services departing from Mission Viejo station and arriving at San Ysidro Station station via San Ysidro Bus Terminal. The journey, including transfers, takes approximately 3h 17m.
Mission Viejo to San Ysidro Station bus services, operated by OCTA, depart from Santa Ana Bus Stop station.
Mission Viejo to San Ysidro Station bus services, operated by OCTA, arrive at San Ysidro Bus Terminal station.
The distance between Mission Viejo and San Ysidro Station is 131.7 km. The road distance is 194 km.
Flixbus USA operates a bus from Santa Ana Bus Stop to San Ysidro Bus Terminal 4 times a day. Tickets cost $16–28 and the journey takes 2h 15m. Greyhound USA also services this route 4 times a day.