The average bus between Missouri and Charlotte takes 24h 8m and the fastest bus takes 20h 55m. The bus service runs several times per day from Missouri to Charlotte. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Missouri and Charlotte. The earliest departure is at 4:10 AM at night, and the last departure from Missouri is at 3:50 PM which arrives into Charlotte at 6:20 PM. All services require a transfer at St Louis Bus Station and take an average of 24h 8m. The schedules shown below are for the next available departures.
Arrives next day


21h 55m • 2 changes
Arrives next day


26h 30m • 2 changes
Arrives next day


21h 55m • 2 changes
Arrives next day


26h 30m • 2 changes
Arrives next day


21h 55m • 2 changes
Arrives next day


26h 30m • 2 changes
Want to know about travelling from Missouri to Charlotte? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Missouri to Charlotte. However, there are services departing from Missouri station and arriving at Charlotte station via St Louis Bus Station station. The journey, including transfers, takes approximately 24h 8m.
Missouri to Charlotte bus services, operated by Greyhound USA, depart from Kansas City Bus Station.
Missouri to Charlotte bus services, operated by Greyhound USA, arrive at Charlotte Bus Station.
Book your Missouri to Charlotte bus tickets online with Greyhound USA and Flixbus USA.
The distance between Missouri and Charlotte is 1,111.4 km. The road distance is 1,694 km.
You can take a bus from Kansas City Bus Station to Charlotte Bus Station via St Louis Bus Station and Atlanta Bus Station in around 21h 40m.