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Missouri to Effingham buses

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Trip Overview

The average bus between Missouri and Effingham takes 6h 45m and the fastest bus takes 6h 20m. The bus service runs several times per day from Missouri to Effingham. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

6h 45m
Duration
347 mi
Distance
$65
Average price
Twice daily
Frequency

Missouri to Effingham bus times

Buses run twice daily between Missouri and Effingham. The earliest departure is at 4:10 AM at night, and the last departure from Missouri is at 8:40 AM which arrives into Effingham at 3:50 PM. All services require a transfer, and take on average 6h 45m. The schedules shown below are for the next available departures.

Departing Saturday, October 10, 2026

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    Greyhound USAGreyhound USA6h 20m • 1 change
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    Greyhound USAGreyhound USA7h 10m • 1 change

Departing Sunday, October 11, 2026

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    Greyhound USAGreyhound USA6h 20m • 1 change
  •  → 

    Greyhound USAGreyhound USA7h 10m • 1 change

Departing Monday, October 12, 2026

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    Greyhound USAGreyhound USA6h 20m • 1 change
  •  → 

    Greyhound USAGreyhound USA7h 10m • 1 change

Departing Tuesday, October 13, 2026

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    Greyhound USAGreyhound USA6h 20m • 1 change
  •  → 

    Greyhound USAGreyhound USA7h 10m • 1 change

Departing Wednesday, October 14, 2026

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    Greyhound USAGreyhound USA6h 20m • 1 change
  •  → 

    Greyhound USAGreyhound USA7h 10m • 1 change

Departing Thursday, October 15, 2026

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    Greyhound USAGreyhound USA6h 20m • 1 change
  •  → 

    Greyhound USAGreyhound USA7h 10m • 1 change

Departing Friday, October 16, 2026

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    Greyhound USAGreyhound USA6h 20m • 1 change
  •  → 

    Greyhound USAGreyhound USA7h 10m • 1 change

Frequently asked questions

Want to know about travelling from Missouri to Effingham? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Missouri to Effingham.ExpandLaunch map view
  • Distance: 347.5 mi
  • Duration: 6h 45m

What companies run services between Missouri, USA and Effingham, IL, USA?

You can take a bus from Kansas City Bus Station to Effingham via St Louis Bus Station in around 6h 45m.

Operators