The average bus between Monroeville and Carlisle takes 8h 37m and the fastest bus takes 7h 16m. The bus service runs several times per day from Monroeville to Carlisle. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Monroeville and Carlisle. The earliest departure is at 6:56 AM in the morning, and the last departure from Monroeville is at 10:01 PM which arrives into Carlisle at 8:37 AM. All services require a transfer at East Busway + Penn Station C and take an average of 8h 37m. The schedules shown below are for the next available departures.


7h 16m • 2 changes
Arrives next day


9h 48m • 2 changes
Arrives next day


10h 35m • 2 changes


7h 18m • 2 changes


7h 54m • 2 changes


7h 16m • 2 changes
Arrives next day


9h 48m • 2 changes


7h 18m • 2 changes


7h 54m • 2 changes


7h 16m • 2 changes
Arrives next day


9h 48m • 2 changes
Want to know about travelling from Monroeville to Carlisle? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Monroeville to Carlisle. However, there are services departing from Monroeville station and arriving at Carlisle station via Harrisburg Bus Station station. The journey, including transfers, takes approximately 8h 37m.
Monroeville to Carlisle bus services, operated by Pittsburgh Regional Transit, depart from Pittsburgh Intermodal Station.
Monroeville to Carlisle bus services, operated by Pittsburgh Regional Transit, arrive at Harrisburg Bus Station.
The distance between Monroeville and Carlisle is 221.7 km. The road distance is 383 km.
Greyhound USA operates a bus from Pittsburgh Intermodal Station to Harrisburg Bus Station every 4 hours. Tickets cost $29–60 and the journey takes 4h 10m. Flixbus USA also services this route twice daily.