The average bus between Montepulciano and Sansepolcro takes 7h 43m and the fastest bus takes 3h 35m. The bus service runs several times per day from Montepulciano to Sansepolcro. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Montepulciano and Sansepolcro. The earliest departure is at 6:14 AM in the morning, and the last departure from Montepulciano is at 7:18 PM which arrives into Sansepolcro at 7:26 AM. All services require a transfer at Sinalunga Stazione and take an average of 7h 43m. The schedules shown below are for the next available departures.


3h 35m • 2 changes


3h 50m • 2 changes
Arrives next day


12h 7m • 2 changes


3h 35m • 2 changes


3h 50m • 2 changes
Arrives next day


12h 7m • 2 changes


3h 35m • 2 changes


3h 50m • 2 changes
Arrives next day


12h 7m • 2 changes


3h 35m • 2 changes


3h 50m • 2 changes
Arrives next day


12h 7m • 2 changes
Want to know about travelling from Montepulciano to Sansepolcro? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Montepulciano to Sansepolcro. However, there are services departing from Montepulciano station and arriving at Sansepolcro station via Arezzo Rfi. The journey, including transfers, takes approximately 7h 43m.
Montepulciano to Sansepolcro bus services, operated by Autolinee Toscane, depart from Sinalunga Rfi station.
Montepulciano to Sansepolcro bus services, operated by Autolinee Toscane, arrive at Sansepolcro Via Marconi station.
The distance between Montepulciano and Sansepolcro is 60.7 km. The road distance is 117 km.
You can take a bus from P.Ta Delle Farine to Sansepolcro Via Marconi via Sinalunga Stazione, Sinalunga Rfi, Arezzo Rfi, and Arezzo Terminal in around 4h 2m.