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Montepulciano to Sicily buses

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Trip Overview

The bus between Montepulciano and Sicily takes 21h 36m. The bus runs, on average, 6 times per week from Montepulciano to Sicily. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

21h 36m
Duration
1,284 km
Distance
€138
Average price
6 times a week
Frequency

Montepulciano to Sicily bus times

Buses run 6 times a week between Montepulciano and Sicily. The service departs Montepulciano at 1:46 PM in the afternoon, which arrives into Sicily at 11:23:00. All services require a transfer at Buonconvento and take an average of 21h 36m. The schedules shown below are for the next available departures.

Departing Monday, November 9, 2026

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    Arrives next day

    Autolinee ToscaneAutolinee ToscaneFlixBusAMAT Palermo S.p.A.21h 36m • 3 changes

Departing Tuesday, November 10, 2026

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    Arrives next day

    Autolinee ToscaneAutolinee ToscaneFlixBusAMAT Palermo S.p.A.21h 36m • 3 changes

Departing Wednesday, November 11, 2026

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    Arrives next day

    Autolinee ToscaneAutolinee ToscaneFlixBusAMAT Palermo S.p.A.21h 36m • 3 changes

Departing Thursday, November 12, 2026

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    Arrives next day

    Autolinee ToscaneAutolinee ToscaneFlixBusAMAT Palermo S.p.A.21h 36m • 3 changes

Departing Friday, November 13, 2026

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    Arrives next day

    Autolinee ToscaneAutolinee ToscaneFlixBusAMAT Palermo S.p.A.21h 36m • 3 changes

Departing Saturday, November 14, 2026

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    Arrives next day

    Autolinee ToscaneAutolinee ToscaneFlixBusAMAT Palermo S.p.A.21h 40m • 3 changes

Frequently asked questions

Want to know about travelling from Montepulciano to Sicily? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Montepulciano to Sicily.ExpandLaunch map view
  • Distance: 1,284.2 km
  • Duration: 21h 36m

What companies run services between Montepulciano, Tuscany, Italy and Sicily, Italy?

You can take a bus from P.Ta Delle Farine to Piazza Boiardo via Buonconvento, Siena, Palermo, and Stazione Centrale Pensilina Esterna in around 19h 47m.

Operators