The average bus between Motta Sant'Anastasia and Palermo takes 4h 59m and the fastest bus takes 4h. The bus service runs several times per day from Motta Sant'Anastasia to Palermo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Motta Sant'Anastasia and Palermo. The earliest departure is at 7:00 AM in the morning, and the last departure from Motta Sant'Anastasia is at 9:30 PM which arrives into Palermo at 11:00 AM. All services require a transfer at Catania and take an average of 4h 59m. The schedules shown below are for the next available departures.

4h • 1 change

5h • 1 change

5h 5m • 1 change

4h 10m • 1 change

4h • 1 change

5h • 1 change

5h 5m • 1 change

4h 10m • 1 change
Want to know about travelling from Motta Sant'Anastasia to Palermo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Motta Sant'Anastasia to Palermo. However, there are services departing from Motta Sant'Anastasia station and arriving at Palermo station via Catania. The journey, including transfers, takes approximately 4h 59m.
Motta Sant'Anastasia to Palermo bus services, operated by Azienda Siciliana Trasporti, depart from Motta Sant' Anastasia station.
Motta Sant'Anastasia to Palermo bus services, operated by Azienda Siciliana Trasporti, arrive at Palermo Via Tommaso Fazello station.
The distance between Motta Sant'Anastasia and Palermo is 159 km. The road distance is 229 km.
You can take a bus from Motta Sant' Anastasia to Palermo Via Tommaso Fazello via Catania and Catania Central Bus Station in around 4h 32m.