Rome2Rio

My Bed Vatican Museum, Rome to Florence buses

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Trip Overview

The average bus between My Bed Vatican Museum, Rome and Florence takes 4h 18m and the fastest bus takes 3h 50m. There is a bus service every few hours from My Bed Vatican Museum, Rome to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 18m
Duration
287 km
Distance
€34
Average price
Hourly
Frequency

My Bed Vatican Museum, Rome to Florence bus times

Buses run hourly between My Bed Vatican Museum, Rome and Florence. The earliest departure is at 5:43 AM in the morning, and the last departure from My Bed Vatican Museum, Rome is at 10:19 PM which arrives into Florence at 2:10 AM. All services require a transfer at Candia/Mocenigo and take an average of 4h 18m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 15m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 10m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 27m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàAutoLinee Moretti5h 9m • 1 change
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Departing Wednesday, November 11, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 22m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 35m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 7m • 1 change
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Departing Thursday, November 12, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 26m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 22m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 35m • 1 change
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Departing Friday, November 13, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 26m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 22m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 35m • 1 change
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Departing Saturday, November 14, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 31m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 12m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 23m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 33m • 1 change
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Departing Sunday, November 15, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 27m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus3h 56m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 4m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 16m • 1 change
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Departing Monday, November 16, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 26m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 22m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus4h 35m • 1 change
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Frequently asked questions

Want to know about travelling from My Bed Vatican Museum, Rome to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from My Bed Vatican Museum, Rome to Florence.ExpandLaunch map view
  • Distance: 286.6 km
  • Duration: 4h 18m

What companies run services between My Bed Vatican Museum, Rome, Italy and Florence, Italy?

FlixBus operates a bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Station hourly. Tickets cost €24–40 and the journey takes 3h 15m. Three other operators also service this route.

Operators