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Myrtle Beach to Guelph buses

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Trip Overview

The average bus between Myrtle Beach and Guelph takes 43h 50m and the fastest bus takes 43h. The bus runs, on average, 3 times per week from Myrtle Beach to Guelph. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

43h 50m
Duration
1,961 km
Distance
$576
Average price
3 times a week
Frequency

Myrtle Beach to Guelph bus times

Buses run 3 times a week between Myrtle Beach and Guelph. The service departs Myrtle Beach at 1:10 PM in the afternoon, which arrives into Guelph at 09:40:00. All services require a transfer at Fayetteville Bus Station and take an average of 43h 50m. The schedules shown below are for the next available departures.

Departing Friday, October 30, 2026

  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USATrailwaysGO Transit45h 30m • 3 changes

Departing Sunday, November 1, 2026

  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USATrailwaysGO Transit43h • 3 changes

Departing Monday, November 2, 2026

  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USATrailwaysGO Transit43h • 3 changes

Frequently asked questions

Want to know about travelling from Myrtle Beach to Guelph? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Myrtle Beach to Guelph.ExpandLaunch map view
  • Distance: 1,961.1 km
  • Duration: 43h 50m

What companies run services between Myrtle Beach, SC, USA and Guelph, ON, Canada?

You can take a bus from Myrtle Beach Bus Station to Guelph Central GO Bus via Fayetteville Bus Station, Newark, Mississauga, and Winston Churchill Transitway Station in around 27h 9m.

Operators