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Myrtle Beach to Louisville buses

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Trip Overview

The bus between Myrtle Beach and Louisville takes 19h 20m. The bus runs, on average, 6 times per week from Myrtle Beach to Louisville. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

19h 20m
Duration
789 mi
Distance
$169
Average price
6 times a week
Frequency

Myrtle Beach to Louisville bus times

Buses run 6 times a week between Myrtle Beach and Louisville. The service departs Myrtle Beach at 12:40 PM in the afternoon, which arrives into Louisville at 08:00:00. All services require a transfer at Atlanta Bus Station and take an average of 19h 20m. The schedules shown below are for the next available departures.

Departing Sunday, November 8, 2026

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    Arrives next day

    Greyhound USAGreyhound USAAmtrak Thruway19h 20m • 2 changes

Departing Monday, November 9, 2026

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    Arrives next day

    Greyhound USAGreyhound USAAmtrak Thruway19h 20m • 2 changes

Departing Tuesday, November 10, 2026

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    Arrives next day

    Greyhound USAGreyhound USAAmtrak Thruway19h 20m • 2 changes

Departing Wednesday, November 11, 2026

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    Arrives next day

    Greyhound USAGreyhound USAAmtrak Thruway19h 20m • 2 changes

Departing Thursday, November 12, 2026

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    Arrives next day

    Greyhound USAGreyhound USAAmtrak Thruway19h 20m • 2 changes

Departing Friday, November 13, 2026

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    Arrives next day

    Greyhound USAGreyhound USAAmtrak Thruway19h 20m • 2 changes

Frequently asked questions

Want to know about travelling from Myrtle Beach to Louisville? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Myrtle Beach to Louisville.ExpandLaunch map view
  • Distance: 788.8 mi
  • Duration: 19h 20m

What companies run services between Myrtle Beach, SC, USA and Louisville, KY, USA?

You can take a bus from Myrtle Beach Bus Station to Louisville, KY via Atlanta Bus Station and Nashville in around 18h 27m.

Operators