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Myrtle Beach to Winston-Salem buses

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Trip Overview

The bus between Myrtle Beach and Winston-Salem takes 17h 35m. The bus runs, on average, 6 times per week from Myrtle Beach to Winston-Salem. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

17h 35m
Duration
323 mi
Distance
$70
Average price
6 times a week
Frequency

Myrtle Beach to Winston-Salem bus times

Buses run 6 times a week between Myrtle Beach and Winston-Salem. The service departs Myrtle Beach at 1:10 PM in the afternoon, which arrives into Winston-Salem at 06:45:00. All services require a transfer, and take on average 17h 35m. The schedules shown below are for the next available departures.

Departing Sunday, November 8, 2026

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    Arrives next day

    Greyhound USAGreyhound USA17h 35m • 1 change

Departing Monday, November 9, 2026

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    Arrives next day

    Greyhound USAGreyhound USA17h 35m • 1 change

Departing Tuesday, November 10, 2026

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    Arrives next day

    Greyhound USAGreyhound USA17h 35m • 1 change

Departing Wednesday, November 11, 2026

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    Arrives next day

    Greyhound USAGreyhound USA17h 35m • 1 change

Departing Thursday, November 12, 2026

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    Arrives next day

    Greyhound USAGreyhound USA17h 35m • 1 change

Departing Friday, November 13, 2026

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    Arrives next day

    Greyhound USAGreyhound USA17h 35m • 1 change

Frequently asked questions

Want to know about travelling from Myrtle Beach to Winston-Salem? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Myrtle Beach to Winston-Salem.ExpandLaunch map view
  • Distance: 323.5 mi
  • Duration: 17h 35m

What companies run services between Myrtle Beach, SC, USA and Winston-Salem, NC, USA?

You can take a bus from Myrtle Beach Bus Station to Winston Salem(Trans Center) via Raleigh Bus Station in around 8h 10m.

Operators