The average bus between Naples and Santa Maria Novella takes 6h 1m and the fastest bus takes 5h 40m. The bus service runs several times per day from Naples to Santa Maria Novella. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Naples and Santa Maria Novella. The earliest departure is at 4:35 PM in the afternoon, and the last departure from Naples is at 11:10 PM which arrives into Santa Maria Novella at 4:50 AM. All services run direct with no transfers required, and take on average 6h 1m. The schedules shown below are for the next available departures.
Arrives next day
Arrives next day
Arrives next day
Arrives next day
Arrives next day
Arrives next day
Arrives next day
Arrives next day
Arrives next day
Arrives next day
Arrives next day
Arrives next day
Arrives next day
Arrives next day
Want to know about travelling from Naples to Santa Maria Novella? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Naples station and arriving at Santa Maria Novella station. Services depart 3 times a day, and operate Once daily. The journey takes approximately 6h 1m.
Naples to Santa Maria Novella bus services, operated by FlixBus, depart from Napoli P.zza Garibaldi station.
Naples to Santa Maria Novella bus services, operated by FlixBus, arrive at Florence station.
Book your Naples to Santa Maria Novella bus tickets online with FlixBus and TTI Leonettibus SRL.
The distance between Naples and Santa Maria Novella is 408.8 km. The road distance is 472 km.
FlixBus operates a bus from Napoli P.zza Garibaldi to Florence 3 times a day. Tickets cost €40–70 and the journey takes 5h 40m. TTI Leonettibus SRL also services this route once a week.