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Nashville to Des Moines buses

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Trip Overview

The bus between Nashville and Des Moines takes 16h 30m. There is at least one bus per day from Nashville to Des Moines. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

16h 30m
Duration
751 mi
Distance
$153
Average price
Once daily
Frequency

Nashville to Des Moines bus times

Buses run once daily between Nashville and Des Moines. The service departs Nashville at 5:15 AM in the morning, which arrives into Des Moines at 21:45:00. All services require a transfer, and take on average 16h 30m. The schedules shown below are for the next available departures.

Departing Sunday, November 8, 2026

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    Greyhound USAGreyhound USA16h 30m • 1 change

Departing Monday, November 9, 2026

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    Greyhound USAGreyhound USA16h 30m • 1 change

Departing Tuesday, November 10, 2026

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    Greyhound USAGreyhound USA16h 30m • 1 change

Departing Wednesday, November 11, 2026

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    Greyhound USAGreyhound USA16h 30m • 1 change

Departing Thursday, November 12, 2026

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    Greyhound USAGreyhound USA16h 30m • 1 change

Departing Friday, November 13, 2026

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    Greyhound USAGreyhound USA16h 30m • 1 change

Departing Saturday, November 14, 2026

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    Greyhound USAGreyhound USA16h 30m • 1 change

Frequently asked questions

Want to know about travelling from Nashville to Des Moines? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Nashville to Des Moines.ExpandLaunch map view
  • Distance: 750.9 mi
  • Duration: 16h 30m

What companies run services between Nashville, TN, USA and Des Moines, IA, USA?

You can take a bus from Nashville Bus Station to Des Moines via Indianapolis Union Station in around 16h 45m.

Operators