- Distance: 317 mi
- Duration: 6h 26m
The average bus between Nashville and St. Louis takes 6h 26m and the fastest bus takes 5h 55m. The bus service runs several times per day from Nashville to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Nashville and St. Louis. The earliest departure is at 3:25 AM at night, and the last departure from Nashville is at 2:50 PM which arrives into St. Louis at 9:30 PM. All services run direct with no transfers required, and take on average 6h 26m. The schedules shown below are for the next available departures.
Want to know about travelling from Nashville to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Nashville station and arriving at St. Louis station. Services depart 3 times a day, and operate Twice daily. The journey takes approximately 6h 26m.
Nashville to St. Louis bus services, operated by Flixbus USA, depart from Nashville Bus Station.
Nashville to St. Louis bus services, operated by Flixbus USA, arrive at St Louis Bus Station.
Book your Nashville to St. Louis bus tickets online with Flixbus USA and Greyhound USA.
The distance between Nashville and St. Louis is 407.2 km. The road distance is 510 km.
Greyhound USA operates a bus from Nashville Bus Station to St Louis Bus Station twice daily. Tickets cost $50–95 and the journey takes 6h 40m. Flixbus USA also services this route 5 times a week.
