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National City to Santa Ana buses

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Trip Overview

The average bus between National City and Santa Ana takes 2h 40m and the fastest bus takes 2h 23m. The bus service runs several times per day from National City to Santa Ana. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2h 40m
Duration
95 mi
Distance
$26
Average price
3 times a day
Frequency

National City to Santa Ana bus times

Buses run 3 times a day between National City and Santa Ana. The earliest departure is at 6:13 AM in the morning, and the last departure from National City is at 6:57 PM which arrives into Santa Ana at 9:20 PM. All services require a transfer at 12th & Imperial Transit Center and take an average of 2h 40m. The schedules shown below are for the next available departures.

Departing Sunday, November 8, 2026

  •  → 

    San Diego Metro TransitGreyhound Mexico2h 32m • 1 change
  •  → 

    San Diego Metro TransitGreyhound Mexico2h 39m • 1 change
  •  → 

    San Diego Metro TransitGreyhound Mexico2h 38m • 1 change

Departing Monday, November 9, 2026

  •  → 

    San Diego Metro TransitGreyhound Mexico2h 57m • 1 change
  •  → 

    San Diego Metro TransitGreyhound Mexico2h 49m • 1 change
  •  → 

    San Diego Metro TransitGreyhound Mexico2h 23m • 1 change

Departing Tuesday, November 10, 2026

  •  → 

    San Diego Metro TransitGreyhound Mexico2h 57m • 1 change
  •  → 

    San Diego Metro TransitGreyhound Mexico2h 49m • 1 change
  •  → 

    San Diego Metro TransitGreyhound Mexico2h 23m • 1 change

Departing Wednesday, November 11, 2026

  •  → 

    San Diego Metro TransitGreyhound Mexico2h 57m • 1 change
  •  → 

    San Diego Metro TransitGreyhound Mexico2h 49m • 1 change
  •  → 

    San Diego Metro TransitGreyhound Mexico2h 23m • 1 change

Departing Thursday, November 12, 2026

  •  → 

    San Diego Metro TransitGreyhound Mexico2h 57m • 1 change
  •  → 

    San Diego Metro TransitGreyhound Mexico2h 49m • 1 change
  •  → 

    San Diego Metro TransitGreyhound Mexico2h 23m • 1 change

Departing Friday, November 13, 2026

  •  → 

    San Diego Metro TransitGreyhound Mexico2h 57m • 1 change
  •  → 

    San Diego Metro TransitGreyhound Mexico2h 49m • 1 change
  •  → 

    San Diego Metro TransitGreyhound Mexico2h 23m • 1 change

Departing Saturday, November 14, 2026

  •  → 

    San Diego Metro TransitGreyhound Mexico2h 32m • 1 change
  •  → 

    San Diego Metro TransitGreyhound Mexico2h 39m • 1 change
  •  → 

    San Diego Metro TransitGreyhound Mexico2h 38m • 1 change

Frequently asked questions

Want to know about travelling from National City to Santa Ana? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from National City to Santa Ana.ExpandLaunch map view
  • Distance: 94.9 mi
  • Duration: 2h 40m

What companies run services between National City, CA, USA and Santa Ana, CA, USA?

Greyhound Mexico operates a bus from San Diego to Santa Ana 3 times a day. Tickets cost $17–26 and the journey takes 1h 55m.

Operators