The average bus between Neu-Isenburg and Heidelberg takes 2h 4m and the fastest bus takes 1h 35m. There is a bus service every few hours from Neu-Isenburg to Heidelberg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between Neu-Isenburg and Heidelberg. The earliest departure is at 4:17 AM at night, and the last departure from Neu-Isenburg is at 11:17 PM which arrives into Heidelberg at 12:19 AM. All services require a transfer at Frankfurt and take an average of 2h 4m. The schedules shown below are for the next available departures.

23 min • 1 change

1h 48m • 1 change

13 min • 1 change

1h 40m • 1 change

2h 12m • 1 change

-7 min • 1 change

23 min • 1 change

13 min • 1 change

2h 12m • 1 change

23 min • 1 change

13 min • 1 change

1 min • 1 change

2h 12m • 1 change

23 min • 1 change

1h 48m • 1 change

13 min • 1 change

2h 12m • 1 change

-7 min • 1 change

23 min • 1 change

1h 48m • 1 change
Want to know about travelling from Neu-Isenburg to Heidelberg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Neu-Isenburg to Heidelberg. However, there are services departing from Neu-Isenburg station and arriving at Heidelberg station via Frankfurt. The journey, including transfers, takes approximately 2h 4m.
Neu-Isenburg to Heidelberg bus services, operated by Kreativ Tours GmbH, depart from Neu-Isenburg Isenburgzentrum Süd station.
Neu-Isenburg to Heidelberg bus services, operated by Kreativ Tours GmbH, arrive at Heidelberg Pre Waypoint station.
The distance between Neu-Isenburg and Heidelberg is 71.2 km. The road distance is 104 km.
You can take a bus from Neu-Isenburg Isenburgzentrum Süd to Heidelberg Pre Waypoint via Frankfurt and Frankfurt Airport in around 2h 25m.