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Neu-Isenburg to Karlsruhe buses

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Trip Overview

The average bus between Neu-Isenburg and Karlsruhe takes 2h 57m and the fastest bus takes 2h 19m. The bus service runs several times per day from Neu-Isenburg to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2h 57m
Duration
160 km
Distance
€16
Average price
Every 3 hours
Frequency

Neu-Isenburg to Karlsruhe bus times

Buses run every 3 hours between Neu-Isenburg and Karlsruhe. The earliest departure is at 4:17 AM at night, and the last departure from Neu-Isenburg is at 11:17 PM which arrives into Karlsruhe at 2:15 AM. All services require a transfer at Frankfurt and take an average of 2h 57m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

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    WEFRA-Bus GbRFlixBus2h 46m • 1 change
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    Arrives next day

    Kreativ Tours GmbHFlixBus3h 58m • 1 change

Departing Thursday, November 12, 2026

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    Kreativ Tours GmbHFlixBus3h 3m • 1 change
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    Kreativ Tours GmbHBlaBlaCar Bus2h 19m • 1 change
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    Kreativ Tours GmbHFlixBus3h 4m • 1 change
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    WEFRA-Bus GbRFlixBus3h 1m • 1 change
  • Show more

Departing Friday, November 13, 2026

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    Kreativ Tours GmbHFlixBus3h 3m • 1 change
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    Kreativ Tours GmbHFlixBus2h 44m • 1 change
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    Kreativ Tours GmbHFlixBus3h 39m • 1 change
  •  → 

    Kreativ Tours GmbHBlaBlaCar Bus2h 19m • 1 change
  • Show more

Departing Saturday, November 14, 2026

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    Kreativ Tours GmbHFlixBus3h 3m • 1 change
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    Kreativ Tours GmbHFlixBus2h 44m • 1 change
  •  → 

    Kreativ Tours GmbHFlixBus3h 39m • 1 change
  •  → 

    Kreativ Tours GmbHBlaBlaCar Bus2h 19m • 1 change
  • Show more

Departing Sunday, November 15, 2026

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    Kreativ Tours GmbHFlixBus3h 3m • 1 change
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    Kreativ Tours GmbHFlixBus2h 44m • 1 change
  •  → 

    Kreativ Tours GmbHFlixBus3h 39m • 1 change
  •  → 

    Kreativ Tours GmbHBlaBlaCar Bus2h 19m • 1 change
  • Show more

Departing Monday, November 16, 2026

  •  → 

    Kreativ Tours GmbHFlixBus3h 3m • 1 change
  •  → 

    Kreativ Tours GmbHFlixBus2h 44m • 1 change
  •  → 

    Kreativ Tours GmbHFlixBus3h 39m • 1 change
  •  → 

    Kreativ Tours GmbHBlaBlaCar Bus2h 19m • 1 change
  • Show more

Departing Tuesday, November 17, 2026

  •  → 

    Kreativ Tours GmbHFlixBus2h 44m • 1 change
  •  → 

    Kreativ Tours GmbHFlixBus3h 39m • 1 change
  •  → 

    Kreativ Tours GmbHBlaBlaCar Bus2h 19m • 1 change
  •  → 

    Kreativ Tours GmbHFlixBus3h 4m • 1 change
  • Show more

Frequently asked questions

Want to know about travelling from Neu-Isenburg to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Neu-Isenburg to Karlsruhe.ExpandLaunch map view
  • Distance: 159.7 km
  • Duration: 2h 57m

What companies run services between Neu-Isenburg, Germany and Karlsruhe, Germany?

FlixBus operates a bus from Frankfurt Airport to Karlsruhe central train station every 2 hours. Tickets cost €13–20 and the journey takes 2h 10m. BlaBlaCar Bus also services this route 4 times a day.

Operators