Neu-Isenburg to Karlsruhe Buses

Neu-Isenburg to Karlsruhe buses

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Trip Overview

The average bus between Neu-Isenburg and Karlsruhe takes 2h 57m and the fastest bus takes 2h 19m. The bus service runs several times per day from Neu-Isenburg to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2h 57m
Duration: 160 km
Distance: €14
Average price: Every 2 hours
Frequency

Bus

best

Take the bus from Frankfurt Airport to Karlsruhe central train stationbus FlixBus 108 / ...

3h 22m

€9–19

Neu-Isenburg to Karlsruhe bus times

Buses run every 2 hours between Neu-Isenburg and Karlsruhe. The earliest departure is at 4:17 AM at night, and the last departure from Neu-Isenburg is at 11:17 PM which arrives into Karlsruhe at 1:15 AM. All services require a transfer at Frankfurt and take an average of 2h 57m. The schedules shown below are for the next available departures.

Departing Saturday, October 10, 2026

7:51 PM → 10:30 PM
2h 39m • 1 change
10:17 PM → 10:50 PM
2h 33m • 1 change
11:17 PM → 1:15 AM
Arrives next day
3h 58m • 1 change

Departing Sunday, October 11, 2026

4:17 AM → 7:20 AM
3h 3m • 1 change
5:21 AM → 6:05 AM
2h 44m • 1 change
7:21 AM → 9:00 AM
3h 39m • 1 change
8:51 AM → 11:10 AM
2h 19m • 1 change
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Departing Monday, October 12, 2026

4:17 AM → 7:20 AM
3h 3m • 1 change
5:21 AM → 6:05 AM
2h 44m • 1 change
7:21 AM → 9:00 AM
3h 39m • 1 change
8:51 AM → 11:10 AM
2h 19m • 1 change
Show more

Departing Tuesday, October 13, 2026

4:17 AM → 7:20 AM
3h 3m • 1 change
5:21 AM → 6:05 AM
2h 44m • 1 change
7:21 AM → 9:00 AM
3h 39m • 1 change
8:51 AM → 11:10 AM
2h 19m • 1 change
Show more

Departing Wednesday, October 14, 2026

7:21 AM → 9:00 AM
3h 39m • 1 change
8:51 AM → 11:10 AM
2h 19m • 1 change
10:21 AM → 11:25 AM
3h 4m • 1 change
6:21 PM → 9:00 PM
2h 39m • 1 change
Show more

Departing Thursday, October 15, 2026

4:17 AM → 7:20 AM
3h 3m • 1 change
7:21 AM → 9:00 AM
3h 39m • 1 change
8:51 AM → 11:10 AM
2h 19m • 1 change
10:21 AM → 11:25 AM
3h 4m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Neu-Isenburg to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

What companies run services between Neu-Isenburg, Germany and Karlsruhe, Germany?

FlixBus operates a bus from Frankfurt Airport to Karlsruhe central train station every 3 hours. Tickets cost €12–19 and the journey takes 2h 10m. BlaBlaCar Bus also services this route 4 times a day.

Operators

Neu-Isenburg to Karlsruhe buses

Find Transport to Karlsruhe

Trip Overview

Bus

Neu-Isenburg to Karlsruhe bus times

Departing Saturday, October 10, 2026

7:51 PM → 10:30 PM

10:17 PM → 10:50 PM

11:17 PM → 1:15 AMArrives next day

Departing Sunday, October 11, 2026

4:17 AM → 7:20 AM

5:21 AM → 6:05 AM

7:21 AM → 9:00 AM

8:51 AM → 11:10 AM

Departing Monday, October 12, 2026

4:17 AM → 7:20 AM

5:21 AM → 6:05 AM

7:21 AM → 9:00 AM

8:51 AM → 11:10 AM

Departing Tuesday, October 13, 2026

4:17 AM → 7:20 AM

5:21 AM → 6:05 AM

7:21 AM → 9:00 AM

8:51 AM → 11:10 AM

Departing Wednesday, October 14, 2026

7:21 AM → 9:00 AM

8:51 AM → 11:10 AM

10:21 AM → 11:25 AM

6:21 PM → 9:00 PM

Departing Thursday, October 15, 2026

4:17 AM → 7:20 AM

7:21 AM → 9:00 AM

8:51 AM → 11:10 AM

10:21 AM → 11:25 AM

Frequently asked questions

What companies run services between Neu-Isenburg, Germany and Karlsruhe, Germany?

Bus from Frankfurt Airport to Karlsruhe central train station

Bus trips from Neu-Isenburg

Bus trips to Karlsruhe

Alternative transport options

11:17 PM → 1:15 AM
Arrives next day