Neu-Isenburg to Karlsruhe Buses

Neu-Isenburg to Karlsruhe buses

Travel from

Search accommodation with Expedia

Trip Overview

The average bus between Neu-Isenburg and Karlsruhe takes 2h 58m and the fastest bus takes 2h 19m. The bus service runs several times per day from Neu-Isenburg to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2h 58m
Duration: 147 km
Distance: €13
Average price: Every 3 hours
Frequency

Bus

best

Take the bus from Frankfurt - Airport Bus Station to Karlsruhe - Central Station South Sidebus BlaBlaCar Bus

2h 45m

€9–17

Neu-Isenburg to Karlsruhe bus times

Buses run every 3 hours between Neu-Isenburg and Karlsruhe. The earliest departure is at 4:17 AM at night, and the last departure from Neu-Isenburg is at 11:17 PM which arrives into Karlsruhe at 1:15 AM. All services require a transfer at Frankfurt and take an average of 2h 58m. The schedules shown below are for the next available departures.

Departing Wednesday, October 14, 2026

10:21 AM → 11:25 AM
3h 4m • 1 change
6:21 PM → 9:00 PM
2h 39m • 1 change
7:39 PM → 8:25 PM
2h 46m • 1 change
11:17 PM → 1:15 AM
Arrives next day
3h 58m • 1 change

Departing Thursday, October 15, 2026

4:17 AM → 7:20 AM
3h 3m • 1 change
8:51 AM → 11:10 AM
2h 19m • 1 change
10:21 AM → 11:25 AM
3h 4m • 1 change
1:09 PM → 2:10 PM
3h 1m • 1 change
Show more

Departing Friday, October 16, 2026

4:17 AM → 7:20 AM
3h 3m • 1 change
5:21 AM → 6:05 AM
2h 44m • 1 change
7:21 AM → 9:00 AM
3h 39m • 1 change
8:51 AM → 11:10 AM
2h 19m • 1 change
Show more

Departing Saturday, October 17, 2026

4:17 AM → 7:20 AM
3h 3m • 1 change
5:21 AM → 6:05 AM
2h 44m • 1 change
7:21 AM → 9:00 AM
3h 39m • 1 change
8:51 AM → 11:10 AM
2h 19m • 1 change
Show more

Departing Sunday, October 18, 2026

4:17 AM → 7:20 AM
3h 3m • 1 change
5:21 AM → 6:05 AM
2h 44m • 1 change
7:21 AM → 9:00 AM
3h 39m • 1 change
8:51 AM → 11:10 AM
2h 19m • 1 change
Show more

Departing Monday, October 19, 2026

4:17 AM → 7:20 AM
3h 3m • 1 change
5:21 AM → 6:05 AM
2h 44m • 1 change

Frequently asked questions

Want to know about travelling from Neu-Isenburg to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Neu-Isenburg to Karlsruhe buses

Trip Overview

Bus