Neu-Isenburg to Karlsruhe Buses

Neu-Isenburg to Karlsruhe buses

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Trip Overview

The average bus between Neu-Isenburg and Karlsruhe takes 2h 57m and the fastest bus takes 2h 19m. The bus service runs several times per day from Neu-Isenburg to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2h 57m
Duration: 160 km
Distance: €15
Average price: Every 3 hours
Frequency

Bus

best

Take the bus from Frankfurt Airport to Karlsruhe central train stationbus FlixBus 108 / ...

3h 29m

€10–19

Neu-Isenburg to Karlsruhe bus times

Buses run every 3 hours between Neu-Isenburg and Karlsruhe. The earliest departure is at 3:17 AM at night, and the last departure from Neu-Isenburg is at 11:17 PM which arrives into Karlsruhe at 1:15 AM. All services require a transfer at Frankfurt and take an average of 2h 57m. The schedules shown below are for the next available departures.

Departing Friday, October 23, 2026

4:17 AM → 7:20 AM
3h 3m • 1 change
5:21 AM → 6:05 AM
2h 44m • 1 change
7:21 AM → 9:00 AM
3h 39m • 1 change
8:51 AM → 11:10 AM
2h 19m • 1 change
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Departing Saturday, October 24, 2026

4:17 AM → 7:20 AM
3h 3m • 1 change
5:21 AM → 6:05 AM
2h 44m • 1 change
7:21 AM → 9:00 AM
3h 39m • 1 change
8:51 AM → 11:10 AM
2h 19m • 1 change
Show more

Departing Sunday, October 25, 2026

3:17 AM → 6:20 AM
3h 3m • 1 change
5:21 AM → 7:05 AM
2h 44m • 1 change
7:21 AM → 10:00 AM
3h 39m • 1 change
8:51 AM → 11:10 AM
2h 19m • 1 change
Show more

Departing Monday, October 26, 2026

4:17 AM → 7:20 AM
3h 3m • 1 change
5:21 AM → 7:05 AM
2h 44m • 1 change
7:21 AM → 10:00 AM
3h 39m • 1 change
8:51 AM → 11:10 AM
2h 19m • 1 change
Show more

Departing Tuesday, October 27, 2026

4:17 AM → 7:20 AM
3h 3m • 1 change
5:21 AM → 7:05 AM
2h 44m • 1 change
7:21 AM → 10:00 AM
3h 39m • 1 change
8:51 AM → 11:10 AM
2h 19m • 1 change
Show more

Departing Wednesday, October 28, 2026

4:17 AM → 7:20 AM
3h 3m • 1 change
7:21 AM → 10:00 AM
3h 39m • 1 change
8:51 AM → 11:10 AM
2h 19m • 1 change
10:21 AM → 12:25 PM
3h 4m • 1 change
Show more

Departing Thursday, October 29, 2026

4:17 AM → 7:20 AM
3h 3m • 1 change
8:51 AM → 11:10 AM
2h 19m • 1 change
10:21 AM → 12:25 PM
3h 4m • 1 change
1:09 PM → 3:10 PM
3h 1m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Neu-Isenburg to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.