Bus Neu-Isenburg to Mannheim | Tickets & Timetables

Neu-Isenburg to Mannheim buses

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Trip Overview

The average bus between Neu-Isenburg and Mannheim takes 1h 40m and the fastest bus takes 1h 25m. There is a bus service every few hours from Neu-Isenburg to Mannheim. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

1h 40m
Duration: 86 km
Distance: Hourly
Frequency

Bus

best

Take the bus from Neu-Isenburg Isenburgzentrum Süd to Frankfurtbus X19
Take the bus from Frankfurt Airport to Mannheim central bus stationbus FlixBus 108 / ...

1h 54m

Neu-Isenburg to Mannheim bus times

Buses run hourly between Neu-Isenburg and Mannheim. The earliest departure is at 3:35 AM at night, and the last departure from Neu-Isenburg is at 11:17 PM which arrives into Mannheim at 11:55 PM. All services require a transfer at Frankfurt and take an average of 1h 40m. The schedules shown below are for the next available departures.

Departing Monday, August 10, 2026

5:21 AM → 4:50 AM
-31 min • 1 change
10:21 AM → 11:55 AM
1h 34m • 1 change
11:51 AM → 1:25 PM
1h 34m • 1 change
3:21 PM → 3:00 PM
-21 min • 1 change
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Departing Tuesday, August 11, 2026

3:35 AM → 5:00 AM
1h 25m • 1 change
4:17 AM → 6:00 AM
1h 43m • 1 change
5:09 AM → 6:45 AM
1h 36m • 1 change
5:21 AM → 4:50 AM
-31 min • 1 change
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Departing Wednesday, August 12, 2026

3:35 AM → 5:00 AM
1h 25m • 1 change
4:17 AM → 6:00 AM
1h 43m • 1 change
5:09 AM → 6:45 AM
1h 36m • 1 change
10:21 AM → 11:55 AM
1h 34m • 1 change
Show more

Departing Thursday, August 13, 2026

3:35 AM → 5:00 AM
1h 25m • 1 change
4:17 AM → 6:00 AM
1h 43m • 1 change
5:09 AM → 6:45 AM
1h 36m • 1 change
10:21 AM → 11:55 AM
1h 34m • 1 change
Show more

Departing Friday, August 14, 2026

3:35 AM → 5:00 AM
1h 25m • 1 change
4:17 AM → 6:00 AM
1h 43m • 1 change
5:09 AM → 6:45 AM
1h 36m • 1 change
5:21 AM → 4:50 AM
-31 min • 1 change
Show more

Frequently asked questions

Want to know about travelling from Neu-Isenburg to Mannheim? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.