The average bus between New York Penn Station and Middletown Amtrak takes 6h 28m and the fastest bus takes 5h 31m. The bus service runs several times per day from New York Penn Station to Middletown Amtrak. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between New York Penn Station and Middletown Amtrak. The earliest departure is at 9:55 AM in the morning, and the last departure from New York Penn Station is at 10:50 PM which arrives into Middletown Amtrak at 7:26 AM. All services require a transfer at Port Authority Bus Terminal and take an average of 6h 28m. The schedules shown below are for the next available departures.

5h 38m • 1 change

6h 49m • 1 change
Arrives next day

6h 52m • 1 change

5h 38m • 1 change

6h 49m • 1 change
Arrives next day

6h 52m • 1 change
Want to know about travelling from New York Penn Station to Middletown Amtrak? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from New York Penn Station to Middletown Amtrak. However, there are services departing from New York Penn Station station and arriving at Middletown Amtrak station via Harrisburg Bus Station station. The journey, including transfers, takes approximately 6h 28m.
New York Penn Station to Middletown Amtrak bus services, operated by Greyhound USA, depart from Port Authority Bus Terminal station.
New York Penn Station to Middletown Amtrak bus services, operated by Greyhound USA, arrive at Harrisburg Bus Station.
The distance between New York Penn Station and Middletown Amtrak is 240.2 km. The road distance is 364 km.
Greyhound USA operates a bus from Port Authority Bus Terminal to Harrisburg Bus Station 5 times a day. Tickets cost $30–65 and the journey takes 3h 35m.