The average bus between New York Penn Station and San Antonio takes 44h 31m and the fastest bus takes 42h 50m. The bus service runs several times per day from New York Penn Station to San Antonio. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between New York Penn Station and San Antonio. The earliest departure is at 10:15 AM in the morning, and the last departure from New York Penn Station is at 10:00 PM which arrives into San Antonio at 3:50 PM. All services require a transfer at 34 St-Herald Sq and take an average of 44h 31m. The schedules shown below are for the next available departures.
Arrives +2 days


43h 10m • 2 changes
Arrives +2 days


41h 50m • 2 changes
Arrives +2 days


43h 10m • 2 changes
Arrives +2 days


41h 50m • 2 changes
Arrives +2 days


43h 10m • 2 changes
Arrives +2 days


41h 50m • 2 changes
Want to know about travelling from New York Penn Station to San Antonio? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from New York Penn Station to San Antonio. However, there are services departing from New York Penn Station station and arriving at San Antonio station via Jackson. The journey, including transfers, takes approximately 44h 31m.
New York Penn Station to San Antonio bus services, operated by Flixbus USA, depart from New York station.
New York Penn Station to San Antonio bus services, operated by Flixbus USA, arrive at Tornado Bus Co - San Antonio station.
Book your New York Penn Station to San Antonio bus tickets online with Flixbus USA and Greyhound USA.
The distance between New York Penn Station and San Antonio is 2,547.6 km. The road distance is 3,036 km.
You can take a vehicle from New York Penn Station to S. St. Mary's & Nueva via 34 St-Herald Sq, East Broadway, New York, Jackson, El Mezcal Grocery - Jackson, TN, Tornado Bus Co - West Memphis, Tornado Bus Co - San Antonio, and I-35 S Access & Yarrow Blvd in around 37h 28m.