The average bus between Niš and Skopje Region takes 4h 46m and the fastest bus takes 4h 12m. The bus service runs several times per day from Niš to Skopje Region. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Niš and Skopje Region. The earliest departure is at 1:07 AM at night, and the last departure from Niš is at 5:45 PM which arrives into Skopje Region at 9:57 PM. All services require a transfer at Skopje, Transporten Centar and take an average of 4h 46m. The schedules shown below are for the next available departures.

5h 10m • 1 change

4h 12m • 1 change

4h 17m • 1 change

4h 19m • 1 change

5h 10m • 1 change

4h 12m • 1 change

4h 17m • 1 change

4h 19m • 1 change

5h 10m • 1 change

4h 12m • 1 change

4h 17m • 1 change

4h 19m • 1 change

5h 10m • 1 change

4h 12m • 1 change

4h 17m • 1 change

4h 19m • 1 change
Want to know about travelling from Niš to Skopje Region? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Niš to Skopje Region. However, there are services departing from Niš station and arriving at Skopje Region station via Skopje, Transporten Centar. The journey, including transfers, takes approximately 4h 46m.
Niš to Skopje Region bus services, operated by Niš-ekspres, depart from Niš, Autobuska Stanica station.
Niš to Skopje Region bus services, operated by Niš-ekspres, arrive at Skopje, Transporten Centar station.
The distance between Niš and Skopje Region is 151.7 km. The road distance is 209 km.
Niš-ekspres operates a bus from Niš, Autobuska Stanica to Skopje, Transporten Centar 5 times a day. Tickets cost $22–40 and the journey takes 3h 57m. AD Galeb Ohrid also services this route once daily.