The average bus between Niagara Falls Station and Syracuse takes 4h 50m and the fastest bus takes 4h. The bus service runs several times per day from Niagara Falls Station to Syracuse. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Niagara Falls Station and Syracuse. The earliest departure is at 12:20 AM at night, and the last departure from Niagara Falls Station is at 11:20 PM which arrives into Syracuse at 3:20 AM. All services require a transfer at Portage Road & NF Transportation Center and take an average of 4h 50m. The schedules shown below are for the next available departures.

4h 35m • 1 change

4h 30m • 1 change

4h 25m • 1 change

4h 20m • 1 change

8h 5m • 1 change

4h 15m • 1 change

4h • 1 change

4h 35m • 1 change

8h 5m • 1 change

4h 15m • 1 change

4h • 1 change

4h 35m • 1 change

8h 5m • 1 change

4h 15m • 1 change

4h • 1 change

4h 35m • 1 change
Want to know about travelling from Niagara Falls Station to Syracuse? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Niagara Falls Station to Syracuse. However, there are services departing from Niagara Falls Station station and arriving at Syracuse station via Ellicott Street & MTC Static. The journey, including transfers, takes approximately 4h 50m.
Niagara Falls Station to Syracuse bus services, operated by NFTA, depart from Portage Road & NF Transportation Center station.
Niagara Falls Station to Syracuse bus services, operated by NFTA, arrive at Syracuse station.
The distance between Niagara Falls Station and Syracuse is 236.2 km. The road distance is 303 km.
You can take a vehicle from Niagara Falls Station to Syracuse via Portage Road & NF Transportation Center and Buffalo in around 5h 26m.