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Niagara Falls to Chicago Bus Station buses

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Trip Overview

The average bus between Niagara Falls and Chicago Bus Station takes 14h 10m and the fastest bus takes 12h 55m. The bus service runs several times per day from Niagara Falls to Chicago Bus Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

14h 10m
Duration
568 mi
Distance
$122
Average price
Twice daily
Frequency

Niagara Falls to Chicago Bus Station bus times

Buses run twice daily between Niagara Falls and Chicago Bus Station. The earliest departure is at 6:03 AM in the morning, and the last departure from Niagara Falls is at 10:04 PM which arrives into Chicago Bus Station at 10:00 AM. All services require a transfer at Ellicott Street & MTC Static and take an average of 14h 10m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Arrives next day

    NFTAGreyhound USAGreyhound USA13h 35m • 2 changes

Departing Thursday, November 12, 2026

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    NFTAGreyhound USAGreyhound USA14h 41m • 2 changes
  •  → 

    Arrives next day

    NFTAGreyhound USAGreyhound USA13h 35m • 2 changes

Departing Friday, November 13, 2026

  •  → 

    NFTAGreyhound USAGreyhound USA14h 41m • 2 changes
  •  → 

    Arrives next day

    NFTAGreyhound USAGreyhound USA13h 35m • 2 changes

Departing Saturday, November 14, 2026

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    NFTAGreyhound USAGreyhound USA15h 1m • 2 changes
  •  → 

    Arrives next day

    NFTAGreyhound USAGreyhound USA12h 55m • 2 changes

Departing Sunday, November 15, 2026

  •  → 

    NFTAGreyhound USAGreyhound USA15h 1m • 2 changes
  •  → 

    Arrives next day

    NFTAGreyhound USAGreyhound USA13h 56m • 2 changes

Departing Monday, November 16, 2026

  •  → 

    NFTAGreyhound USAGreyhound USA14h 41m • 2 changes
  •  → 

    Arrives next day

    NFTAGreyhound USAGreyhound USA13h 35m • 2 changes

Departing Tuesday, November 17, 2026

  •  → 

    NFTAGreyhound USAGreyhound USA14h 41m • 2 changes

Frequently asked questions

Want to know about travelling from Niagara Falls to Chicago Bus Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Niagara Falls to Chicago Bus Station.ExpandLaunch map view
  • Distance: 567.9 mi
  • Duration: 14h 10m

What companies run services between Niagara Falls, NY, USA and Chicago Bus Station, IL, USA?

You can take a bus from Pine Avenue & Main Street to Chicago Bus Station via Ellicott Street & MTC Static, Buffalo, and Cleveland Bus Station in around 13h 42m.

Operators