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Niagara Falls to Chicago Union Station buses

Find Transport to Chicago Union Station

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Trip Overview

The average bus between Niagara Falls and Chicago Union Station takes 20h 24m and the fastest bus takes 13h 7m. The bus runs, on average, 2 times per week from Niagara Falls to Chicago Union Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

20h 24m
Duration
576 mi
Distance
Twice a week
Frequency

Niagara Falls to Chicago Union Station bus times

Buses run twice a week between Niagara Falls and Chicago Union Station. The earliest departure is at 6:03 AM in the morning, and the last departure from Niagara Falls is at 10:04 PM which arrives into Chicago Union Station at 10:12 AM. All services require a transfer at Ellicott Street & MTC Static and take an average of 20h 24m. The schedules shown below are for the next available departures.

Departing Saturday, November 7, 2026

  •  → 

    Arrives next day

    NFTAGreyhound USAGreyhound USAAmtrak27h 41m • 3 changes
  •  → 

    Arrives next day

    NFTAGreyhound USAGreyhound USAAmtrak13h 7m • 3 changes

Frequently asked questions

Want to know about travelling from Niagara Falls to Chicago Union Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Niagara Falls to Chicago Union Station.ExpandLaunch map view
  • Distance: 576.2 mi
  • Duration: 20h 24m

What companies run services between Niagara Falls, NY, USA and Chicago Union Station, IL, USA?

You can take a bus from Pine Avenue & Main Street to Chicago Union Station via Ellicott Street & MTC Static, Buffalo, Cleveland Bus Station, and Toledo in around 13h 24m.

Operators