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Niagara Falls to Florence buses

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Trip Overview

The bus between Niagara Falls and Florence takes 23h 50m. The bus runs, on average, 4 times per week from Niagara Falls to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

23h 50m
Duration
1,052 mi
Distance
$200
Average price
4 times a week
Frequency

Niagara Falls to Florence bus times

Buses run 4 times a week between Niagara Falls and Florence. The service departs Niagara Falls at 9:50 AM in the morning, which arrives into Florence at 09:40:00. All services require a transfer at Newark Penn Station and take an average of 23h 50m. The schedules shown below are for the next available departures.

Departing Monday, November 2, 2026

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    Arrives next day

    Flixbus USAFlixbus USAGreyhound USA23h 50m • 2 changes

Departing Tuesday, November 3, 2026

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    Arrives next day

    Flixbus USAFlixbus USAGreyhound USA23h 50m • 2 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives next day

    Flixbus USAFlixbus USAGreyhound USA23h 50m • 2 changes

Departing Saturday, November 7, 2026

  •  → 

    Arrives next day

    Flixbus USAFlixbus USAGreyhound USA23h 50m • 2 changes

Frequently asked questions

Want to know about travelling from Niagara Falls to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Niagara Falls to Florence.ExpandLaunch map view
  • Distance: 1,052.4 mi
  • Duration: 23h 50m

What companies run services between Niagara Falls, NY, USA and Florence, SC, USA?

You can take a bus from Niagara Falls USA to Florence Bus Station via Newark Penn Station and Fayetteville Bus Station in around 22h 20m.

Operators