The average bus between Niagara Falls and Middletown takes 13h 35m and the fastest bus takes 9h 25m. The bus service runs several times per day from Niagara Falls to Middletown. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Niagara Falls and Middletown. The earliest departure is at 9:50 AM in the morning, and the last departure from Niagara Falls is at 11:20 PM which arrives into Middletown at 8:45 AM. All services require a transfer at Binghamton ShortLine Terminal and take an average of 13h 35m. The schedules shown below are for the next available departures.
Arrives next day


20h 55m • 2 changes
Arrives next day


9h 25m • 2 changes
Arrives next day


20h 55m • 2 changes
Arrives next day


9h 25m • 2 changes
Want to know about travelling from Niagara Falls to Middletown? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Niagara Falls to Middletown. However, there are services departing from Niagara Falls station and arriving at Middletown station via Binghamton. The journey, including transfers, takes approximately 13h 35m.
Niagara Falls to Middletown bus services, operated by Flixbus USA, depart from Niagara Falls USA station.
Niagara Falls to Middletown bus services, operated by Flixbus USA, arrive at Railroad Ave - Middletown Terminal station.
The distance between Niagara Falls and Middletown is 423 km. The road distance is 596 km.
You can take a bus from Niagara Falls USA to Railroad Ave - Middletown Terminal via Binghamton ShortLine Terminal and Monticello ShortLine Terminal in around 9h 50m.