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Niagara Falls to Millsboro buses

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Trip Overview

The average bus between Niagara Falls and Millsboro takes 27h 24m and the fastest bus takes 23h 17m. The bus runs, on average, 3 times per week from Niagara Falls to Millsboro. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

27h 24m
Duration
643 mi
Distance
$113
Average price
3 times a week
Frequency

Niagara Falls to Millsboro bus times

Buses run 3 times a week between Niagara Falls and Millsboro. The earliest departure is at 9:50 AM in the morning, and the last departure from Niagara Falls is at 9:20 PM which arrives into Millsboro at 6:08 AM. All services require a transfer at Newark Penn Station and take an average of 27h 24m. The schedules shown below are for the next available departures.

Departing Saturday, November 7, 2026

  •  → 

    Arrives +2 days

    Flixbus USAGreyhound USADART First StateDART First State32h 48m • 3 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    Flixbus USAGreyhound USADART First StateDART First State26h 6m • 3 changes
  •  → 

    Arrives next day

    Flixbus USAGreyhound USADART First StateDART First State23h 17m • 3 changes

Frequently asked questions

Want to know about travelling from Niagara Falls to Millsboro? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Niagara Falls to Millsboro.ExpandLaunch map view
  • Distance: 643.4 mi
  • Duration: 27h 24m

What companies run services between Niagara Falls, NY, USA and Millsboro, DE, USA?

You can take a bus from Niagara Falls USA to Monroe St At Brandywine Village Apts via Newark Penn Station, Wilmington Bus Station, Wilmington Tc, and Rehoboth P-N-R @ Country Club Rd in around 16h 20m.

Operators