The average bus between Niagara Falls and Upper East Side takes 9h 55m and the fastest bus takes 9h 33m. The bus service runs several times per day from Niagara Falls to Upper East Side. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Niagara Falls and Upper East Side. The earliest departure is at 2:50 AM at night, and the last departure from Niagara Falls is at 11:20 PM which arrives into Upper East Side at 9:17 AM. All services require a transfer at New York Midtown and take an average of 9h 55m. The schedules shown below are for the next available departures.

10h 1m • 1 change
Arrives next day

9h 37m • 1 change
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9h 57m • 1 change

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9h 56m • 1 change

9h 55m • 1 change

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10h 3m • 1 change

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9h 47m • 1 change

9h 48m • 1 change

9h 56m • 1 change

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9h 45m • 1 change

9h 50m • 1 change

9h 53m • 1 change

10h 10m • 1 change

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10h 3m • 1 change
Want to know about travelling from Niagara Falls to Upper East Side? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Niagara Falls to Upper East Side. However, there are services departing from Niagara Falls station and arriving at Upper East Side station via New York Midtown. The journey, including transfers, takes approximately 9h 55m.
Niagara Falls to Upper East Side bus services, operated by Flixbus USA, depart from Niagara Falls USA station.
Niagara Falls to Upper East Side bus services, operated by Flixbus USA, arrive at New York Midtown station.
The distance between Niagara Falls and Upper East Side is 494.5 km. The road distance is 780 km.
Jefferson Lines operates a bus from Niagara Falls USA to New York Midtown every 3 hours. Tickets cost $110–160 and the journey takes 9h 5m. Flixbus USA also services this route every 4 hours.