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Niagara Falls to Wayne buses

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Trip Overview

The average bus between Niagara Falls and Wayne takes 16h 14m and the fastest bus takes 13h 33m. The bus service runs several times per day from Niagara Falls to Wayne. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

16h 14m
Duration
451 mi
Distance
$121
Average price
3 times a day
Frequency

Niagara Falls to Wayne bus times

Buses run 3 times a day between Niagara Falls and Wayne. The earliest departure is at 2:50 AM at night, and the last departure from Niagara Falls is at 9:20 PM which arrives into Wayne at 10:53 AM. All services require a transfer at Ellicott Street & MTC Static and take an average of 16h 14m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

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    Arrives next day

    Flixbus USAFlixbus USASEPTASEPTA13h 33m • 3 changes

Departing Wednesday, November 11, 2026

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    Flixbus USAGreyhound USASEPTASEPTA14h 3m • 3 changes
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    Arrives next day

    Flixbus USAGreyhound USASEPTASEPTA21h 22m • 3 changes
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    Arrives next day

    Flixbus USAFlixbus USASEPTASEPTA16h 37m • 3 changes

Departing Thursday, November 12, 2026

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    Arrives next day

    Flixbus USAGreyhound USASEPTASEPTA19h 52m • 3 changes
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    Arrives next day

    Flixbus USAFlixbus USASEPTASEPTA16h 37m • 3 changes

Departing Friday, November 13, 2026

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    Flixbus USAGreyhound USASEPTASEPTA14h 6m • 3 changes
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    Arrives next day

    Flixbus USAGreyhound USASEPTASEPTA20h 50m • 3 changes
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    Arrives next day

    Flixbus USAFlixbus USASEPTASEPTA17h 25m • 3 changes

Departing Saturday, November 14, 2026

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    Flixbus USAGreyhound USASEPTASEPTA13h 55m • 3 changes
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    Flixbus USAGreyhound USASEPTASEPTA13h 54m • 3 changes

Departing Sunday, November 15, 2026

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    Arrives next day

    Flixbus USAGreyhound USASEPTASEPTA19h 52m • 3 changes
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    Arrives next day

    Flixbus USAFlixbus USASEPTASEPTA16h 37m • 3 changes

Departing Monday, November 16, 2026

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    Flixbus USAGreyhound USASEPTASEPTA14h 3m • 3 changes
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    Flixbus USAGreyhound USASEPTASEPTA14h 6m • 3 changes

Frequently asked questions

Want to know about travelling from Niagara Falls to Wayne? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Niagara Falls to Wayne.ExpandLaunch map view
  • Distance: 450.6 mi
  • Duration: 16h 14m

What companies run services between Niagara Falls, NY, USA and Wayne, PA, USA?

You can take a bus from Pine Avenue & Main Street to Wayne via Ellicott Street & MTC Static, Buffalo, Scranton, Philadelphia 30th St Station, and Gray 30th St Station in around 12h 46m.

Operators